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DOUXO® Chlorhexidine

A cleansing treatment to help provide relief from itching and inflammation associated with skin infections responsive to chlorhexidine and climbazole.

DOUXO® is the #1 non-prescription topical brand used and recommended by U.S. veterinarians for the treatment of dogs and cats with infections/inflammatory dermatological diseases.1


DOUXO® Chlorhexidine Shampoo is a formulation designed for the antiseptic cleansing of the skin of dogs and cats. It is soap-free and contains gentle cleansing agents and moisturizers.

DOUXO® Chlorhexidine Shampoo also contains Phytosphingosine, a pro-ceramide to help rebuild natural ceramides in the skin that are critical in helping keep the skin healthy.

If you have difficulty bathing your pet, DOUXO® Chlorhexidine Shampoo can be used alongside DOUXO® Chlorhexidine Mousse or DOUXO® Chlorhexidine Micro-emulsion Spray. 

DOUXO®   Chlorhexidine Micro-emulsion Spray and Shampoo protocol along with antibiotic treatment helps improve skin and coat health within 7 days vs. antibiotic treatment alone (as reported by pet owners).2


This is a soap-free, low-lather shampoo. Do not over-apply.

Before bathing, gently remove all tangles and mats. Use cool water to wet your pet’s fur from the neck down avoiding the eyes and inside of ears. Place a small amount of shampoo on your hands and gently massage onto areas of the body with skin abnormalities. Next, massage shampoo on the remainder of the body, sparing the head and ears. Ensure shampoo reaches the skin. Leave the shampoo on for 10 minutes. Rinse with cool water until the water runs clear.

Cautions: For external use on dogs and cats only. Avoid contact with the eyes. In case of contact with eyes, rinse thoroughly and consult your veterinarian. If irritation occurs or increases, discontinue use and consult with your veterinarian.

Key Ingredients :

  • Chlorhexidine gluconate 3%: an antibacterial and antifungal agent.
  • Climbazole 0.5%: an antifungal agent.
  • Phytosphingosine salicyloyl 0.05%: phytosphingosine (PS) is found naturally in the stratum corneum and some skin ceramides. PS applied topically can help restore the skin barrier.

DOUXO®  products do not contain paraben.

Available Sizes:

  • 200 mL, 500 mL or 3 L

1.BIO’SAT Quantitative Study of 250 veterinarians geographically representative of North American practices.   Dermatology Products for Cats and Dogs Among Veterinary Practitioners.  October 2018.

2.  Study conducted in France using EU formulation comparing the efficacy of an antibiotic plus DOUXO® topical therapy vs. antibiotic treatment alone. Clinical efficacy of DOUXO® Chlorhexidine Shampoo + DOUXO® Chlorhexidine Micro-emulsion Spray protocol in controlling superficial pyoderma in dogs in combination with cefalexin, compared to cefalexin alone.

Related Products


DOUXO®  Chlorhexidine helps manage skin infections responsive to chlorhexidine and climbazole*.   Cleans, soothes and repairs the skin barrier. *Micro-emulsion spray does not contain climbazole.

DOUXO® is the #1 non-prescription topical brand used and recommended by U.S. veterinarians for dogs and cats with infections/inflammatory dermatological disease.1