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DOUXO® ® Calm protects the skin barrier. It soothes and hydrates itchy, irritated, and sensitive skins while balancing skin microflora too.

The latest scientific data confirm that protecting the skin barrier ecosystem is a critical element in the management of skin issues. In pets as in humans, it is particularly important in sensitive, itchy and irritated skin problems.

What is DOUXO® Calm?

Just like people your pet can show allergic symptoms to everyday substances.

DOUXO® Calm replenishes the barrier that helps to protect your pet from allergens and improves skin hydration.
The skin becomes more supple which reduces the itching.

DOUXO® Calm is clinically proven to help decrease itch and irritation in sensitive skins.


DOUXO® Calm contains Phytosphingosine

DOUXO® Calm, as the entire DOUXO® range, contains the patented molecule Phytosphingosine. It is a fundamental component of ceramides, complex lipids, found naturally in the skin which helps the cohesion of the skin barrier.

Phytosphingosine is a key player in skin functions and helps protect the skin barrier ecosystem by:

  • Supporting the cohesion of the mechanical skin barrier
  • Soothing and hydrating
  • Helping balance microflora 

Pseudofilaggrin for an enhanced activity on the skin barrier

Skin of atopic dogs presents a filaggrin defect. 

Filaggrin is a protein that permits skin cells to mature and become the strong corneocytes that protect the body from outside. Filaggrin also has a direct role in moisturization: it degrades producing NMF (Natural Moisturizing Factor) which is essential to skin hydration. We can compare filaggrin to a sponge that helps retain the water in the skin.

DOUXO® Calm Shampoo and Mousse contain Pseudofilaggrin that boosts the profilaggrin synthesis and that ensures impermeability of skin barrier.

Protocol for use

Use every 3 days


 Optimal results: start protocol with Shampoo,

then every 3 days use the Mousse.


Once a day

For localized applications, directly spray the Serum without touching the irritated skin.

DOUXO® Calm products: