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DOUXO®  S3 CALM helps to soothe irritated and itchy skin. It is formulated to soothe and hydrate the skin.  It detangles the fur and leaves the hair coat soft and shiny.  

DOUXO® is the #1 non-prescription topical brand used and recommended by US veterinarians for dogs & cats with allergic dermatitis.1

DOUXO®  S3 CALM Mousse is for dogs or cats with itchy, irritated skin.  

DOUXO® S3 CALM Mousse contains OPHYTRIUM™ (Ophiopogon japonicus Root Extract), a purified, natural ingredient carefully selected for its high tolerance and simultaneous threefold action on the skin's ecosystem.

  • Helps support the skin's physical barrier for supple, hydrated skin
  • Helps support the microbial flora for healthy skin
  • Helps soothe irritated skin

FREE from controversial ingredients.

DOUXO® S3 products are free from:

  • Soaps
  • Sulfates
  • Parabens
  • Phthalates
  • Colorants
  • Nanoparticles

DOUXO® S3 CALM Mousse has a hypoallergenic fragrance and adjusted pH.  It was formulated and tested by veterinary dermatology experts.

Clinically Proven.

DOUXO®  S3 CALM has been clinically proven to reduce the extent and severity of the signs of Canine Atopic Dermatitis by 58%2.  

DOUXO®  S3 CALM has been clinically proven to help reduce itching in dogs with Atopic Dermatitis by 41%.  Results were seen within 7 days, with best results after 21 days.2


DOUXO®  S3 CALM shampoo and mousse are meant to be used together in a clinically proven and consumer-friendly protocol.  Apply to a brushed, dry coat.  First, gently massage onto the problem area until the mousse reaches the skin.  Repeat this action all over the body, avoid the eyes and mouth.  Do not rinse.  Let air dry.  Brush for a shiny coat.  Use DOUXO® S3 CALM Shampoo to clean the skin if needed.

  • Dogs < 13 lbs  1 pump per 2 lbs
  • Dogs > 13 lbs   1 pump per 4 lbs
  • Double the dosage for long and/or thick fur.

Note: Approximately 200 pumps per bottle

Available Size:

  • 150 mL (5.1 fl oz)

Cautions: For external use on dogs or cats only. Avoid contact with the eyes. In case of contact with eyes, rinse thoroughly and consult your veterinarian. If irritation occurs or increases, discontinue use and consult with your veterinarian.

1.BIO’SAT Quantitative Study of 250 veterinarians geographically representative of North American practices.   Dermatology Products for Cats and Dogs Among Veterinary Practitioners.  October 2018.

2. Gatellet, M., Kesteman, R., Blondel, T., Zemirline, C., Ollivier, E., & De-Jaeger, X. (2020).  Performance of a combination of Ophytrium0containing shampoo and mousse applications in the management of sensitive skin in dogs:  intermediate results of a field study.  14th UNISVET National Congress.  Milan, Italy.

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DOUXO®  S3 CALM helps to soothe and hydrate itchy, irritated skin.