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DOUXO® Calm aids skin balance and protects the skin barrier ecosystem. It soothes and hydrates itchy, irritated, sensitive skins while balancing skin microflora which is commonly unbalanced in sensitive skins. 

The latest scientific data confirm that protecting the skin barrier ecosystem is a critical element in the management of skin issues. In pets as in humans, it is particularly important in sensitive, itchy and irritated skin problems.

What is DOUXO® Calm?

Just like people your pet can show allergic symptoms to everyday substances.

DOUXO® Calm replenishes the barrier that protects your pet from allergens and irritants and improves skin hydratation between day 0 and day 21 (see chart). The skin becomes more supple which reduces the sensations of itching.

DOUXO® Calm is clinically proven to help to decrease itch and irritation in sensitive skins.

Skin hydratation rate - DOUXO® Calm Shampoo & Mousse

DOUXO® Calm contains Phytosphingosine

DOUXO® Calm, as the entire DOUXO® range, contains the patented molecule Phytosphingosine. It is a fundamental component of ceramides, complex lipids, found naturally in the skin and ensuring the cohesion of the skin barrier.

Phytosphingosine is a key player in skin functions and helps protect the skin barrier ecosystem:

  • Supports the cohesion of the mechanical skin barrier
  • Soothes and hydrates
  • Helps balance microflora 

Pseudofilaggrin for an enhanced activity on the skin barrier

Skin of atopic dogs presents a filaggrin defect. 

Filaggrin is a protein that permits to skin cells to mature and become the strong corneocytes that protect the body from outside. Filaggrin has also a direct role in moisturization: it degrades producing NMF (Natural Moisturizing Factor) which is essential to skin hydration. We can compare filaggrin to a sponge that helps retain the water in the skin.

DOUXO® Calm Shampoo and Mousse contain Pseudofilaggrin that boosts the profilaggrin synthesis and that guarantees impermeability of skin barrier.

Protocol for use

Use 1 every 3 days


 Optimal results: start protocol with Shampoo,

then every 3 days use either Mousse or Micro-Emulsion spray.


Once a day

For localized applications, directly spray the Serum without touching the irritated skin.

DOUXO® Calm products: